BS3 Crosslinker disodium ( —— )

Catalog No. M22834 CAS No. 127634-19-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BS3 Crosslinker disodium
Note

Research use only, not for human use.
Brief Description

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Description

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Synonyms

——
Pathway

Antibody Drug Conjugates (ADC)
Target

ADCs Linker/Click Chemistry
Recptor

Non-cleavable
Research Area

——
Indication

——

CAS Number

127634-19-9
Formula Weight

572.43
Molecular Formula

C16H18N2Na2O14S2
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (218.37 mM; Need ultrasonic)
SMILES

O=S(C(C1)C(N(OC(CCCCCCC(ON2C(C(S(=O)([O-])=O)CC2=O)=O)=O)=O)C1=O)=O)([O-])=O.[Na+].[Na+]
Chemical Name

——

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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