BS3 Crosslinker disodium( —— )

Catalog No. M22834 CAS No. 127634-19-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BS3 Crosslinker disodium
Note

Research use only, not for human use.
Brief Description

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Description

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Antibody Drug Conjugates (ADC)
Target

ADCs Linker/Click Chemistry
Recptor

Non-cleavable
Research Area

——
Indication

——

CAS Number

127634-19-9
Formula Weight

572.43
Molecular Formula

C16H18N2Na2O14S2
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (218.37 mM; Need ultrasonic)
SMILES

O=S(C(C1)C(N(OC(CCCCCCC(ON2C(C(S(=O)([O-])=O)CC2=O)=O)=O)=O)C1=O)=O)([O-])=O.[Na+].[Na+]
Chemical Name

——

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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